Overview and Introduction:  Viral Definition

• Viral Structure

• Viral Symmetry

• Viral Envelopes

  • Viral Structural Proteins

  • Viral Lipids

  • Viral Capsid Assembly

    • Genome Packaging

  • Viral Capsid and Core Proteins

Viral Genome Classification

• Nucleic Acid Strandedness

• Repetitive Elements

• 5'-Terminal Cap

• 5'-Terminal Covalently-Linked Protein

• Isomerization

• 3'-Terminal Poly(A) Tract

• Genomic Organization and Replication

  • Gene Order

  • Open Reading Frames

Viral Replication

• Viral-Cell Membrane Fusion

  • Enfuvirtide (Fuzeon):  Example Drug

    • Enfurvirtide Pharmacology

  • Maraviroc (Selzentry, Celsentri):  Example Drug

    • Miraviroc Pharmacology

• Viral Gene Expression and Viral Replication

• Replication of DNA Viral Genomes

• Baltimore Classification System