Medical Pharmacology Chapter 36:  Antiviral Drugs

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Protease Inhibitors

 

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References

  1. Wang F Kieff E Medical Viriology, Cahpter 177 Section 11:  Viral Diseases:  General Considerations (in Harrison's Principles of Internal Medicine, 18th edition, Longo DF Fauci AS Kasper DL Hauser SL Jameson JL Loscalzo J, eds) McGraw-Hill, New York, 2012, pp 1432-1433.

  2. Lu K Gulick RM (Based on a presentation at PRN by Roy M. Gulick, MD, MPH New antiretrovirals for the treatment of HIV;  the view in 2006.  The PRN Notebook 11(2) October 2006. The figure corresponds to Figure 2 in this reference and was derived by the authors from an original image by Robert W. Doms, MD, Ph.D. The figure in on this page has been slightly modified from its original form in reference 8.

  3. Flexner C Chapter 59.  Antiretroviral Agents and Treatment of HIV Infection (in Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12 e, Brunton LL Chabner BA Knollmann BC, eds) The McGraw-Hill Companies, Inc, 2011.

  4. Safrin S Chapter 49:  Antiviral Agents:  Antiretroviral Agents in Basic & Clinical Pharmacology 13e (Katzung BG Trevor AJ, eds) 2015, online edition.

  5. AIDSinfo:  Guidelines for the Use of Antriretroviral Agents in HIV-1-Infected Adults and Adolescents https://aidsinfo.nih.gov/guidelines (2015)

  6. Tsibris AMN Hirsch MS Chapter 130 Antiretroviral Therapy for Human Immunodeficiency Virus Infection in Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 8e (Bennett JE Bolin R Blaser, eds) Elsevier, Inc/Saunders 2015, online version.

  7. LaBonte J Lebbos J Kirkpatrick nature Reviews Drug Discovery 2, 345-346 (May 2003). (Slight modification of Fig. 1) http://www.nature.com/nrd/journal/v2/n5/fig_tab/nrd1091_F1.html; Original figure attribution:  Kilby JM Hopkins S Venetta TM

  8. Woster PM Antiviral Agents and Protease Inhibitors.  Chapter 43  in Foye's Principles of Medicinal Chemistry, 6e Lemke TL; Williams DA, eds; Roche VF Zito SW, asst. eds), Lippincott Williams & Wilkins, a Wolters Kluwer business, 1219, 2008.

  9. Swaminathan J and MSD staff at the European Bioinformatics Institute  (http://www.ebi.ac.uk/) Renin:  molecular structure registered with 2rn code. https://commons.wikimedia.org/wiki/File:PDB_2ren_EBI.jpg

  10. Renin:  https://en.wikipedia.org/wiki/Renin

  11. Haggstrom M "Overview of the renin-angiotensin system" https://commons.wikimedia.org/wiki/File:Renin-angiotensin_system_in_man_shadow.svg

  12. Flexner C HIV-Protease Inhibitors The New England Journal of Medicine 338(18) 1281-1292, April 30, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9562584

  13. MLGProGamer123 "Cartoon structure of HIV enzyme" "HIV-1 Protease with Active Site" https://commons.wikimedia.org/wiki/File:HIV-1_Protease_with_Active_Site.png

  14. HIV-1 Protease https://en.wikipedia.org/wiki/HIV-1_protease

  15. Jaskolski M Tomasselli AG Sawyer TK Staples DG Heinrikson RL Schneider J Kent SBH Wlodawer Structure at 2.5 A Resolution of Chemically Synthesized Human Immunodeficiency Virus Type I Protease Complexed with a Hydroxyethylene-Based Inhibitor. Biochemistry 30, 1600-1609, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1993177

  16. Mansur C Rena de Freitas R Rabelo FT Mansur L Rabelo FT Monteiro Santiago FC de Oliveira T Azevedo FQ Redistribution of body fat induced by HIV protease inhibitors in patients with AIDS.  An. Bras. Dermatol. vol. 81 suppl.3 Rio De Janeiro Sept/Oct 2006, Case report. http://www.scielo.br/scielo.php?pid=S0365-05962006000900015&script=sci_arttext&tlng=en

  17. Wensing AM Calvez V Gunthard JF Johnson VA Paredes R Pillay D Shafer RW Richman DD Special Contribution:  2014 Update of the Drug Resistance Multations in HIV-1 Topics in Antivral Medicine 22(3)  June/July 2014, https://www.iasusa.org/sites/default/files/tam/22-3-642.pdf

  18. Garg A Acquired and Inherited Lipodystrophies.  N Engl J Med 350:  1220-1234 2004. http://www.ncbi.nlm.nih.gov/pubmed/15028826

 

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