Medical Pharmacology Clinical Case:  Calcium Channel Blockers and Dopamine in Heart Disease

 

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  • A 58 year-old man has been in progressive coronary insufficiency for at least five years, with angina of effort and recent early signs of left ventricular failure.

  • Cardiac catherization revealed atherosclerotic obstruction of both the left anterior descending and circumflex arteries.

  • Coronary artery bypass graft (CABG) operation schedule, since cardiac failure appeared imminent.

  • The patient was on a daily regimen of nicardipine at the time of surgery.




  • case author: Hugh S. Mathewson,
    M.D., Professor Emeritus, School of Allied
    Health, Department of Nurse Anesthesia,
    University of Kansas Medical Center

  • case editor: Michael Gordon, Ph.D. Associate
    Professor of Pharmacology and Surgery, School of
    Medicine, Department of Pharmacology, University
    of Kansas Medical Center