| 
| 1 | This antihypertensive drug is contraindicated in patients with bilateral renal artery stenosis: | 
 | 
 | 
 | 
clonidine (Catapres) | 
 | 
 | 
 | 
terazosin (Hytrin) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
captopril (Capoten) | 
 | 
 | 
 | 
metoprolol (Lopressor) | 
 
 | 
| 2 | Antihypertensive drug typically used in patients with severe hypertension and renal insufficiency; this agent produces significant fluid retention and hypertrichosis. | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
methyldopa (Aldomet) | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
diltiazem (Cardiazem) | 
 
 | 
| 3 | The drug of choice in management of hypertensive crisis when continuously variable IV infusion is required. | 
 | 
 | 
 | 
lisinopril (Prinvivil, Zestril) | 
 | 
 | 
 | 
diazoxide (Hyperstat) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
metoprolol (Lopressor) | 
 
 | 
| 4 | A drug-induced lupus-like syndrome is associated with this antihypertensive drug | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
diazoxide (Hyperstat) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
acebutolol (Sectral) | 
 
 | 
| 5 | Tachycardia due to hydralazine administration would be blocked by: | 
 | 
 | 
 | 
bumetanide (Bumex) | 
 | 
 | 
 | 
fosinopril (Monopril) | 
 | 
 | 
 | 
mecamylamine (Inversine) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 
 | 
| 6 | A diabetic patient is prescribed a new medication to control mild hypertension.  The patient then becomes less aware of hypoglycemic symptoms.  The antihypertensive drug was most probably: | 
 | 
 | 
 | 
phentolamine (Regitine) | 
 | 
 | 
 | 
atenolol (Tenormin) | 
 | 
 | 
 | 
enalapril (Vasotec) and | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
prazosin (Minipress) | 
 
 | 
| 7 | Which drug would be least likely used in the initial pharmacological treatment of mild hypertension? | 
 | 
 | 
 | 
amlodipine (Norvasc) | 
 | 
 | 
 | 
metoprolol (Lopressor) | 
 | 
 | 
 | 
enalapril (Vasotec) | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
chlorothiazide (Diuril) | 
 
 | 
| 8 | Which antihypertensive drug would be contraindicated if the patient were taking tranylcypromine (Parnate)? | 
 | 
 | 
 | 
hydrochlorothiazide (HCTZ, Esidrix, HydroDIURIL) | 
 | 
 | 
 | 
diltiazem (Cardiazem) | 
 | 
 | 
 | 
guanethidine (Ismelin) | 
 | 
 | 
 | 
lisinopril (Prinvivil, Zestril) | 
 | 
 | 
 | 
labetalol (Trandate, Normodyne) | 
 
 | 
| 9 | Which drug would block the antihypertensive efficacy of guanadrel (Hylorel)? | 
 | 
 | 
 | 
buspirone (BuSpar) | 
 | 
 | 
 | 
lorazepam (Ativan) | 
 | 
 | 
 | 
imipramine (Tofranil) | 
 | 
 | 
 | 
propranolol (Inderal) | 
 | 
 | 
 | 
chlorothiazide (Diuril) | 
 
 | 
| 10 | Lisinopril belongs to which class of antihypertensive drugs? | 
 | 
 | 
 | 
centrally-acting sympatholytic | 
 | 
 | 
 | 
beta-adrenoceptor antagonist | 
 | 
 | 
 | 
angiotensin II receptor antagonist | 
 | 
 | 
 | 
beta-adrenoceptor agonist | 
 | 
 | 
 | 
angiotensin II converting enzyme inhibitor | 
 
 | 
| 11 | Most likely to be used for initial drug management of moderate hypertension | 
 | 
 | 
 | 
guanethidine (Ismelin) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 
 | 
| 12 | Antihypertensive agents -- side effect profile includes impaired glucose tolerance, hypokalemia, increased serum lipids and increased renin secretion: | 
 | 
 | 
 | 
methyldopa (Aldomet) | 
 | 
 | 
 | 
chlorothiazide (Diuril) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
diazoxide (Hyperstat) | 
 
 | 
| 13 | Effects of hydralazine (Apresoline): | 
 | 
 | 
 | 
increased renin levels | 
 | 
 | 
 | 
lupus-like syndrome | 
 | 
 | 
 | 
reflex bradycardia | 
 | 
 | 
 | 
hypertensive response if patient ingests food rich in tyramine | 
 | 
 | 
 | 
all of the above | 
 
 | 
| 14 | Mechanisms by which blood-pressure may be reduced: | 
 | 
 | 
 | 
reduced cardiac output | 
 | 
 | 
 | 
increased vagus nerve activity | 
 | 
 | 
 | 
decreased central sympathetic outflow | 
 | 
 | 
 | 
reduced angiotensin II levels | 
 | 
 | 
 | 
all the above | 
 
 | 
| 15 | Orthostatic hypotension: | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
imipramine (Tofranil) | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
methyldopa (Aldomet) | 
 | 
 | 
 | 
all of the above | 
 
 | 
| 16 | Antihypertensive drug least likely to cause orthostatic hypotension: | 
 | 
 | 
 | 
minoxidil (Loniten) | 
 | 
 | 
 | 
enalapril (Vasotec) | 
 | 
 | 
 | 
guanethidine (Ismelin) | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
terazosin (Hytrin) | 
 
 | 
| 17 | Vascular smooth muscle relaxation by means of calcium channel blockade: | 
 | 
 | 
 | 
hydralazine (Apresoline) | 
 | 
 | 
 | 
nitroprusside sodium (Nipride) | 
 | 
 | 
 | 
nifedipine (Procardia, Adalat) | 
 | 
 | 
 | 
captopril (Capoten) | 
 | 
 | 
 | 
phentolamine (Regitine) | 
 
 | 
| 18 | Protects against tachycardia caused by minoxidil (Loniten) administration: | 
 | 
 | 
 | 
prazosin (Minipress) | 
 | 
 | 
 | 
diltiazem (Cardiazem) | 
 | 
 | 
 | 
metoprolol (Lopressor) | 
 | 
 | 
 | 
losartin (Cozaar) | 
 | 
 | 
 | 
methyldopa (Aldomet) | 
 
 | 
| 19 | Mechanism of antihypertensive action:inhibition of peptidyl dipeptidase | 
 | 
 | 
 | 
metoprolol (Lopressor) | 
 | 
 | 
 | 
verapamil (Isoptin, Calan) | 
 | 
 | 
 | 
lisinopril (Prinvivil, Zestril) | 
 | 
 | 
 | 
diazoxide (Hyperstat) | 
 
 | 
| 20 | Antihypertensive agent that can produce a positive Coombs' test | 
 | 
 | 
 | 
clonidine (Catapres) | 
 | 
 | 
 | 
guanabenz (Wytensin) | 
 | 
 | 
 | 
guanfacine (Tenex) | 
 | 
 | 
 | 
methyldopa (Aldomet) | 
 | 
 | 
 | 
all the above | 
 
 |