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Medical Pharmacology Chapter 9: Coronary Artery Disease Practice Questions Practice Questions

 

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Question # 1 (Multiple Answer) Vasodilators that may mediate local myocardial control of coronary vascular tone

    A) adenosine
    B) bradykinin
    C) prostaglandins
    D) potassium ions
    E) hydrogen ions

Question # 2 (Multiple Choice) Amino acid precursor for nitric oxide:

    A) methionine
    B) arginine
    C) aspartate
    D) phenylalanine
    E) dopamine

Question # 3 (Multiple Choice) Calcium channel blockers: inotropic effects --

    A) increased inotropism
    B) decreased inotropism

Question # 4 (Multiple Choice) Angina associated with coronary vasospasm:

    A) exertional angina
    B) Prinzmetal's angina (variant)

Question # 5 (Multiple Answer) Homeostatic activities of nitric oxide:

    A) cardiovascular tone
    B) gastrointestinal smooth muscle relaxation
    C) immune regulation
    D) platelet regulation
    E) CNS signaling

Question # 6 (Multiple Answer) Associated with predominantly cardiac effects:

    A) amlodipine (Norvasc)
    B) diltiazem (Cardiazem)
    C) nifedipine (Procardia, Adalat)
    D) verapamil (Isoptin, Calan)

Question # 7 (Multiple Answer) Increased myocardial oxygen requirements:

    A) increased myocardial wall tension
    B) decreased contractile state
    C) increased heart rate

Question # 8 (Multiple Answer) Mechanism(s) explaining calcium channel blocker effectiveness in managing exertional angina:

    A) decreased contractility
    B) decreased afterload
    C) decreased preload
    D) increased coronary blood flow

Question # 9 (Multiple Choice) More likely to influence myocardial contractility:

    A) diltiazem (Cardiazem)
    B) nifedipine (Procardia, Adalat)

Question # 10 (Multiple Choice) More likely to have an effect on AV nodal conduction:

    A) diltiazem (Cardiazem)
    B) amlodipine (Norvasc)

Question # 11 (Multiple Answer) Commonly use nitrates for management of classical angina:

    A) sublingual nitroglycerin
    B) transdermal nitroglycerin
    C) isosorbide dinitrate (Isordil, Sorbitrate)
    D) isosorbide-5-mononitrate

Question # 12 (Multiple Answer) Effective antianginal drug(s):

    A) propranolol (Inderal)
    B) timolol (Blocadren)
    C) esmolol (Brevibloc)
    D) metoprolol (Lopressor)
    E) atenolol (Tenormin)

Question # 13 (Multiple Answer) Associate with predominately vascular effects:

    A) amlodipine (Norvasc)
    B) verapamil (Isoptin, Calan)
    C) nicardipine (Cardene)
    D) diltiazem (Cardiazem)

Question # 14 (Multiple Choice) Beta adrenergic receptor blockers are beneficial in managing angina because they:

    A) reduced angina frequency
    B) reduced severity of exertional angina attacks
    C) both
    D) neither

Question # 15 (True/False) Major mistake: administration of verapamil (IV) to patient with ventricular tachycardia which was missed diagnosed as supraventricular arrhythmia:

    A) true
    B) false

Question # 16 (Multiple Answer) Pharmacological actions associated with calcium channel blockers that tend to diminish angina:

    A) decreased afterload
    B) increased heart rate
    C) decreased myocardial wall tension
    D) decreased preload

Question # 17 (Multiple Choice) Relatively little effects on myocardial contractility compared to verapamil:

    A) amlodipine (Norvasc)
    B) felodipine (Plendil)
    C) both
    D) neither

Question # 18 (Multiple Answer) Nitrates: smooth muscle relaxation -- noncardiac sites:

    A) Sphincter of Oddi
    B) biliary duct
    C) bronchioles
    D) esophageal
    E) uterine smooth muscle

Question # 19 (Multiple Answer) Mechanism(s) responsible for antianginal effects of beta-blockers:

    A) increased heart rate
    B) decreased contractility
    C) decreased blood pressure during exercise

Question # 20 (Multiple Choice) Cardioselective beta-blocker:

    A) propranolol (Inderal)
    B) metoprolol (Lopressor)
    C) both
    D) neither

Question # 21 (Multiple Answer) Causes of myocardial ischemia:

    A) coronary vessel atherosclerosis
    B) arterial thrombi
    C) reduced preload
    D) coronary vasospasm
    E) decreased afterload

Question # 22 (Multiple Choice) Nitric oxide half-life:

    A) less than five seconds
    B) about a minute
    C) ten minutes
    D) an hour
    E) longer than one-hour

Question # 23 (Multiple Answer) Physiological effects of low-dose nitrates:

    A) increased end-diastolic right ventricular pressure
    B) decreased left ventricular chamber size
    C) arteriolar dilation

Question # 24 (True/False) Verapamil (Isoptin, Calan)-- major use other than for management of angina: treating reentrant super ventricular tachycardia

    A) true
    B) false

Question # 25 (Multiple Answer) Pharmacological interventions for management of angina:

    A) nitrates
    B) beta- agonists
    C) calcium channel blockers
    D) antimuscarinics

Question # 26 (Multiple Choice) Control of coronary blood flow involves:

    A) local metabolism
    B) nervous system regulation
    C) both
    D) neither

Question # 27 (Multiple Answer) May cause worsening of myocardial ischemia:

    A) amlodipine (Norvasc)
    B) nimodipine (Nimotop)
    C) nifedipine (Procardia, Adalat)
    D) nicardipine (Cardene)
    E) felodipine (Plendil)

Question # 28 (Multiple Choice) More appropriate for treating variant angina:

    A) propranolol (Inderal)
    B) diltiazem (Cardiazem)

Question # 29 (Multiple Answer) Examples of beta adrenergic receptor blockers used in management of chronic, classical angina:

    A) propranolol (Inderal)
    B) isoproterenol (Isuprel)
    C) nadolol (Corgard)
    D) atenolol (Tenormin)
    E) doxepin (Sinequan)

Question # 30 (Multiple Answer) Side effects associated with calcium channel blockade:

    A) hypertension
    B) dizziness
    C) flushing
    D) nausea

Correct Answers

1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30






































Question # 1 (Multiple Answer) Vasodilators that may mediate local myocardial control of coronary vascular tone

(A) adenosine

(B) bradykinin

(C) prostaglandins

(D) potassium ions

(E) hydrogen ions

BACK







































Question # 2 (Multiple Choice) Amino acid precursor for nitric oxide:

Answer: (B) arginine

BACK







































Question # 3 (Multiple Choice) Calcium channel blockers: inotropic effects --

Answer: (B) decreased inotropism

BACK







































Question # 4 (Multiple Choice) Angina associated with coronary vasospasm:

Answer: (B) Prinzmetal's angina (variant)

BACK







































Question # 5 (Multiple Answer) Homeostatic activities of nitric oxide:

(A) cardiovascular tone

(B) gastrointestinal smooth muscle relaxation

(C) immune regulation

(D) platelet regulation

(E) CNS signaling

BACK







































Question # 6 (Multiple Answer) Associated with predominantly cardiac effects:

(B) diltiazem (Cardiazem)

(D) verapamil (Isoptin, Calan)

BACK







































Question # 7 (Multiple Answer) Increased myocardial oxygen requirements:

(A) increased myocardial wall tension

(C) increased heart rate

BACK







































Question # 8 (Multiple Answer) Mechanism(s) explaining calcium channel blocker effectiveness in managing exertional angina:

(A) decreased contractility

(B) decreased afterload

(D) increased coronary blood flow

BACK







































Question # 9 (Multiple Choice) More likely to influence myocardial contractility:

Answer: (A) diltiazem (Cardiazem)

BACK







































Question # 10 (Multiple Choice) More likely to have an effect on AV nodal conduction:

Answer: (A) diltiazem (Cardiazem)

BACK







































Question # 11 (Multiple Answer) Commonly use nitrates for management of classical angina:

(A) sublingual nitroglycerin

(B) transdermal nitroglycerin

(C) isosorbide dinitrate (Isordil, Sorbitrate)

(D) isosorbide-5-mononitrate

BACK







































Question # 12 (Multiple Answer) Effective antianginal drug(s):

(A) propranolol (Inderal)

(B) timolol (Blocadren)

(D) metoprolol (Lopressor)

(E) atenolol (Tenormin)

BACK







































Question # 13 (Multiple Answer) Associate with predominately vascular effects:

(A) amlodipine (Norvasc)

(C) nicardipine (Cardene)

BACK







































Question # 14 (Multiple Choice) Beta adrenergic receptor blockers are beneficial in managing angina because they:

Answer: (C) both

BACK







































Question # 15 (True/False) Major mistake: administration of verapamil (IV) to patient with ventricular tachycardia which was missed diagnosed as supraventricular arrhythmia:

Answer: True

BACK







































Question # 16 (Multiple Answer) Pharmacological actions associated with calcium channel blockers that tend to diminish angina:

(A) decreased afterload

(C) decreased myocardial wall tension

BACK







































Question # 17 (Multiple Choice) Relatively little effects on myocardial contractility compared to verapamil:

Answer: (C) both

BACK







































Question # 18 (Multiple Answer) Nitrates: smooth muscle relaxation -- noncardiac sites:

(A) Sphincter of Oddi

(B) biliary duct

(C) bronchioles

(D) esophageal

(E) uterine smooth muscle

BACK







































Question # 19 (Multiple Answer) Mechanism(s) responsible for antianginal effects of beta-blockers:

(B) decreased contractility

(C) decreased blood pressure during exercise

BACK







































Question # 20 (Multiple Choice) Cardioselective beta-blocker:

Answer: (B) metoprolol (Lopressor)

BACK







































Question # 21 (Multiple Answer) Causes of myocardial ischemia:

(A) coronary vessel atherosclerosis

(B) arterial thrombi

(D) coronary vasospasm

BACK







































Question # 22 (Multiple Choice) Nitric oxide half-life:

Answer: (A) less than five seconds

BACK







































Question # 23 (Multiple Answer) Physiological effects of low-dose nitrates:

(B) decreased left ventricular chamber size

(C) arteriolar dilation

BACK







































Question # 24 (True/False) Verapamil (Isoptin, Calan)-- major use other than for management of angina: treating reentrant super ventricular tachycardia

Answer: True

BACK







































Question # 25 (Multiple Answer) Pharmacological interventions for management of angina:

(A) nitrates

(C) calcium channel blockers

BACK







































Question # 26 (Multiple Choice) Control of coronary blood flow involves:

Answer: (C) both

BACK







































Question # 27 (Multiple Answer) May cause worsening of myocardial ischemia:

(A) amlodipine (Norvasc)

(B) nimodipine (Nimotop)

(C) nifedipine (Procardia, Adalat)

(D) nicardipine (Cardene)

(E) felodipine (Plendil)

dihydropyridine --secondary to tachycardia BACK







































Question # 28 (Multiple Choice) More appropriate for treating variant angina:

Answer: (B) diltiazem (Cardiazem)

BACK







































Question # 29 (Multiple Answer) Examples of beta adrenergic receptor blockers used in management of chronic, classical angina:

(A) propranolol (Inderal)

(C) nadolol (Corgard)

(D) atenolol (Tenormin)

BACK







































Question # 30 (Multiple Answer) Side effects associated with calcium channel blockade:

(B) dizziness

(C) flushing

(D) nausea

BACK