used in patients with ventricular tachycardia or fibrillation resistant to treatment with other drugs.

effective inhibitor of abnormal automaticity.

blocks sodium and potassium channels and prolongs action potential duration.

most serious adverse effect seen in long-term therapy is a rapidly progressive pulmonary fibrosis which may be fatal

potent inhibitor of hepatic metabolism or renal elimination of many drugs.

Warfarin, quinidine, procainamide and digoxin are examples of drugs which may require dosage reduction during amiodarone administration.