Chloramphenicol: (Chloromycetin)
- serious
rickettsial infections (typhus or Rocky Mountain spottend fever)
in children under 8 (when tetracyclines are contraindicated)
- Alternative
treatment for bacterial meningitis due to a very
penicillin-resistant pneumococcal isolate
- Meningococcal
infections in patients with significant penicillin
hypersensitivity.
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Tetracycline
A
tetracycline is the drug of choice for treating these
infections:
- Mycoplasma
pneumoniae
- chlamydiae
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- rickettsia
- some
spirochetes.
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- Used in combination
with other drugs to treat gastric and duodenal
ulcer casue by Helicobacter pylori.
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Erythromycin
- Erythromycin is the drug
of choice in treatment corynebacterial infections
(diphtheria, corynebacterial sepsis, erythrasma)
- in respiratory,
neonatal, ocular or genital chlamydia infections
- community-acquired
pneumonia because its broad spectrum of treatment
of action allows effective treatment of
pneumoncoccus, Mycoplasma and Legionella
- Erythromycin:
penicillin-substitute for patients allergic to
penicillin
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Clindamycin: (Cleocin)
- Primary, important
indication for clindamycin: severe anaerobic
infections due to Bacterioides
and other anaerobes in mixed infections.
- prophylaxis:
Clindamycin instead of erythromycin for
endocarditis prior to dental procedures on
patients who have valvular diseas
- Clindamycin +
primaquine: effective alternative to
trimethoprim-sulfamethoxazole (Bactrim) in
treating moderate to moderately-severe Pneumocystis
carinii pneumonia in AIDS patients.
- Clindamycin (Cleocin):
useful in treating AIDS-related CNS toxoplasmosis
in combination with pyrimethamine (Daraprim).
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