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Diabetes I

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Question # 1 (Multiple Choice) Less likely to cause hepatotoxicity
A) rosiglitazone (Avandia)
B) troglitazone (Rezulin)
C) both equally hepatotoxic

Question # 2 (Multiple Answer) Second generation sulfonylurea
A) chlorpropamide (Diabinese)
B) tolazamide (Tolinase)
C) glimepiride (Amaryl)
D) glyburide (Micronase, DiaBeta)

Question # 3 (Multiple Answer) Complications of insulin treatment:
A) tachycardia
B) tremor
C) palpitations
D) hunger
E) mental confusion

Question # 4 (Multiple Answer) Biguanides: clinical uses & advantages:
A) does not increase weight
B) does not cause hypoglycemia
C) used in patients with refractory obesity
D) used in patients with insulin resistance

Question # 5 (Multiple Answer) oral hypoglycemics: categories
A) sulfonylureas -- glipizide (Glucotrol)
B) biguanides -- metformin (Glucophage)
C) alpha glucosidase inhibitor -- actor boasts
D) thiozolidinediones -- rosiglitazone (Avandia)

Question # 6 (Multiple Answer) Treatment of severe hypoglycemia (unconscious patient) --
A) IV glucose infusion
B) 1 mg glucagon

Question # 7 (Multiple Choice) Adverse effects associated with acarbose (Precose)
A) hypoglycemia if used in combination with insulin or sulfonylureas
B) flatulence
C) both
D) neither

Question # 8 (True/False) Diabetic retinopathy is the leading cause of blindness in United States:
A) true
B) false

Question # 9 (Multiple Choice) Glyburide (Micronase, DiaBeta) -- contraindicated in:
A) hepatic impairment
B) renal insufficiency
C) both
D) neither

Question # 10 (Multiple Answer) Troglitazone (Rezulin):
A) withdrawn for use as monotherapy
B) approved for use in insulin-resistant patients receiving insulin
C) increases tissue insulin sensitivity
D) may cause rare, but occasionally lethal liver dysfunction

Question # 11 (Multiple Answer) Presenting symptoms of IDDM:
A) oligouria
B) polydipsia
C) polyphagia

Question # 12 (Multiple Answer) Characteristics of autonomic neuropathy associated with diabetes:
A) syncope
B) cardiopulmonary arrest
C) orthostatic hypotension
D) constipation or diarrhea
E) esophageal dysfunction

Question # 13 (True/False) Renal disease is the leading cause of death and disability due to diabetes
A) true
B) false