Anti-inflammatory Question Set #2:

Matching exercise

Pick the best match from the options (click on down arrow at the right)

mediator of acute inflammation ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin mediator of chronic inflammation ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin cell type: source for the chronic inflammation mediator TNF alpha ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin Primary Effect of TNF alpha in chronic inflammation: ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin may slow bone damage associated with rheumatoid arthritis ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin reduces pharmacological activity of spironolactone, competes with penicillin G. for renal tubular secretion;inhibits probenecid uricosuric effect ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin celecoxib ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin salicylate, but less effective than aspirin as cyclooxygenase inhibitors ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin transaminitis (increase serum aminotransferase) ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin infusion of this drug: accelerates closure of patent ductus arteriosus in premature newborns ??? enhancements of prostaglandin production leukotrienes interferons macrophages methotrexate indomethacin (Indocin) magnesium choline salicylate diclofenac (Voltaren) COX-II inhibitor aspirin

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