Previous Page

 
 
 

 

Medical Pharmacology:  Autacoids Practice Test Questions

This is a self-grading exam. Answers are entered by clicking the button corresponding to your selection. The examination is scored by clicking 'Grade Test' at the bottom of the form. Correct answers are found through hyperlinks at the bottom of the page.



Question # 1 (Multiple Answer) CNS serotonin:

    A) mood
    B) sleep
    C) appetite
    D) pain perception
    E) vomiting

Question # 2 (True/False) Propofol (Diprivan) for induction and maintenance of anesthesia may be as effective as ondansetron (Zofran) in reducing/preventing postoperative emesis

    A) true
    B) false

Question # 3 (Multiple Choice) Serotonin overproduction (carcinoid tumor):

    A) constipation
    B) diarrhea

Question # 4 (Multiple Choice) Major clinical use(s): cyproheptadine (Periactin):

    A) reduces smooth muscle effects of carcinoid tumor
    B) reduces postgastrectomy dumping syndrome
    C) both
    D) neither

Question # 5 (Multiple Choice) Widely distributed indoleethylamine formed from tryptophan:

    A) epinephrine
    B) nicotine
    C) serotonin
    D) leukotriene
    E) prostaglandins

Question # 6 (True/False) Serotonin -- gastrointestinal tract effects:decreased peristalsis

    A) true
    B) false

Question # 7 (Multiple Choice) Antiemetic agent with least side effects

    A) chlorpromazine (Thorazine)
    B) butyrophenones
    C) ondansetron (Zofran)
    D) diphenhydramine (Benadryl)

Question # 8 (Multiple Choice) Serotonin: platelet effects --

    A) promotes aggregation
    B) inhibits aggregation

Question # 9 (Multiple Choice) Greater than 90% of serotonin is located here:

    A) platelets
    B) raphe nucleus (brain stem)
    C) enterochromaffin cells of the GI tract
    D) lung
    E) cerebral cortex

Question # 10 (Multiple Answer) Cardiovascular effects of serotonin:

    A) skeletal muscle vasculature: vasodilatation
    B) reflex bradycardia
    C) pulmonary and renal vasculature: vasoconstriction

Question # 11 (Multiple Answer) Sumatriptan (Imitrex) and migraine:

    A) relieves symptoms for few patients
    B) efficacy greater than or equal to other drug treatments
    C) multiple dosing may be required

Question # 12 (Multiple Answer) Serotonin agonists -- clinical use:

    A) buspirone -- anxiolytic
    B) sumatriptan (Imitrex) -- antimigraine; anti-cluster headaches
    C) both
    D) neither

Question # 13 (Multiple Answer) Serotonin: nervous system --

    A) stimulates itch and pain sensory nerve endings
    B) activates chemosensitive nerve endings in coronary vessels
    C) atropine-sensitive bradycardia
    D) activates medullary vomiting reflex (5 HT3)

Question # 14 (Multiple Choice) ondansetron (Zofran), granisetron (Kytril), tropisetron interact with its serotonin receptor subtype located in the area postrema, sensory, and enteric nerves:

    A) 5 HT1a
    B) 5 HT1d
    C) 5 HT3
    D) 5 HT4

Question # 15 (Multiple Choice) Sumatriptan (Imitrex) -- contraindications

    A) presence of ischemic heart disease
    B) patients have variant (Prinzmetal's) angina
    C) both
    D) neither

Question # 16 (Multiple Answer) Ondansetron (Zofran) -- pharmacology:

    A) activates dopamine (Intropin), histamine and adrenergic receptors
    B) very effective for prevention of nausea iand vomiting caused by chemotherapy or surgery
    C) reduces postoperative vomiting in patients following middle ear surgery

Question # 17 (Multiple Answer) Adverse effects -- sumatriptan (Imitrex)

    A) muscle weakness
    B) chest pain
    C) dizziness
    D) altered sensations (tingling, warmth recurrent

Correct Answers

1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17






































Question # 1 (Multiple Answer) CNS serotonin:

(A) mood

(B) sleep

(C) appetite

(D) pain perception

(E) vomiting

BACK







































Question # 2 (True/False) Propofol (Diprivan) for induction and maintenance of anesthesia may be as effective as ondansetron (Zofran) in reducing/preventing postoperative emesis

Answer: True

BACK







































Question # 3 (Multiple Choice) Serotonin overproduction (carcinoid tumor):

Answer: (B) diarrhea

BACK







































Question # 4 (Multiple Choice) Major clinical use(s): cyproheptadine (Periactin):

Answer: (C) both

BACK







































Question # 5 (Multiple Choice) Widely distributed indoleethylamine formed from tryptophan:

Answer: (C) serotonin

BACK







































Question # 6 (True/False) Serotonin -- gastrointestinal tract effects:decreased peristalsis

Answer: False

BACK







































Question # 7 (Multiple Choice) Antiemetic agent with least side effects

Answer: (C) ondansetron (Zofran)

BACK







































Question # 8 (Multiple Choice) Serotonin: platelet effects --

Answer: (A) promotes aggregation

BACK







































Question # 9 (Multiple Choice) Greater than 90% of serotonin is located here:

Answer: (C) enterochromaffin cells of the GI tract

BACK







































Question # 10 (Multiple Answer) Cardiovascular effects of serotonin:

(A) skeletal muscle vasculature: vasodilatation

(B) reflex bradycardia

(C) pulmonary and renal vasculature: vasoconstriction

BACK







































Question # 11 (Multiple Answer) Sumatriptan (Imitrex) and migraine:

(B) efficacy greater than or equal to other drug treatments

(C) multiple dosing may be required

BACK







































Question # 12 (Multiple Answer) Serotonin agonists -- clinical use:

(C) both

BACK







































Question # 13 (Multiple Answer) Serotonin: nervous system --

(A) stimulates itch and pain sensory nerve endings

(B) activates chemosensitive nerve endings in coronary vessels

(C) atropine-sensitive bradycardia

(D) activates medullary vomiting reflex (5 HT3)

BACK







































Question # 14 (Multiple Choice) ondansetron (Zofran), granisetron (Kytril), tropisetron interact with its serotonin receptor subtype located in the area postrema, sensory, and enteric nerves:

Answer: (C) 5 HT3

BACK







































Question # 15 (Multiple Choice) Sumatriptan (Imitrex) -- contraindications

Answer: (C) both

BACK







































Question # 16 (Multiple Answer) Ondansetron (Zofran) -- pharmacology:

(B) very effective for prevention of nausea iand vomiting caused by chemotherapy or surgery

(C) reduces postoperative vomiting in patients following middle ear surgery

BACK







































Question # 17 (Multiple Answer) Adverse effects -- sumatriptan (Imitrex)

(A) muscle weakness

(B) chest pain

(C) dizziness

(D) altered sensations (tingling, warmth recurrent

BACK