Anesthesia Pharmacology:  ANS 
Introduction Practice Questions
	Choose the correct answer for each question.
 
 
 
- Sympathetic nervous system anatomy and properties: -   gangionic neurotransmitter: acetylcholine
-   generalized response upond sympathetic stimulation
-   thoraco-lumbar origin for preganglionic cell bodies
-   all of the above
 
- Comparing autonomic and somatic nerves: -   somatic nerves, like autonomic nerves contain ganglia.
-   Most of the fibers in the vagus nerve ar sensory
-   denervated smooth muscle show spontaneous activity
-   motor nerves are typically unmyelinated.
 
- Major anatomical site for integration of autonomic information: -   cerebellum
-   sensory cortex
-   hypothalamus
-   spinal cord--dorsal horn
 
- Division of the autonomic nervous system associated with diffuse autonomic responses. -   sympathetic
-   parasympathetic
-   both
-   neither
 
- Activation of the sympathetic nervous system will caus which change in the skeletal muscle versus cutaneous vascular beds. -   vasoconstriction, vasoconstriction
-   vasodilatation, vasodilatation
-   vasodilatation, vasoconstriction
-   vasoconstriction, vasodilation
 
- Adrenergic receptor type(s) mediating pupillary dilation -   beta-2
-   alpha-1
-   muscarinic
-   serotonergic
 
- Cholinergic receptor type that mediates vasodilation following low-dose i.v. acetylcholine administration: -   nicotinic
-   muscarinic
-   nitric oxide receptor
-   substance P receptor
 
- "True" acetylcholinesterase is found in: -   glia
-   liver
-   erythrocytes
-   plasma
 
- Catalyzes rate-limiting step in catecholamine biosynthesis: -   DOPA decarboxylase
-   phenylethanolamine N-methyl transferase
-   tyrosine hydroxylase
-   dopamine-beta-hydroxylase
 
- Inhibited by drugs such as phenelzine or tranylcypromine; -   COMT (catechol-O-methyl transferase)
-   MAO (monoamine oxidase)
-   choline acetyltransferase
-   reuptake-I inhibitor
 
- Concentation increased by epinephrine: -   blood free fatty acids
-   blood glucose
-   skeletal muscle glycogen
-   A & B
 
- Due to receptor specificity, catecholamine LEAST likely to produce bronchiolar smooth muscle relaxation: -   epinephrine
-   terbutaline (Brethine)
-   phenylephrine
-   phentolamine (Regitine)
 
- Alpha adrenergic receptor blocker -   phentolamine (Regitine)
-   phenoxybenzamine (Dibenzyline)
-   terbutaline (Brethine)
-   A & B
 
- Covalent inhibitor of acetylcholinesterse: -   edrophonium (Tensilon)
-   diisopropylphosphate (DFP)
-   atropine
-   muscarine
 
- Alpha-adenergic receptor agonist: -   terbutaline (Brethine)
-   atropine
-   methoxamine (Vasoxyl)
-   isoproterenol (Isuprel)
 
- Parasympathetic direct cardiac effects: -   decrease heart rate; increase contractility
-   increase heart rate; decrease contractility
-   decrease heart rate; decrease contractility
-   increase AV nodal conduction velocity
 
- Choline ester substrate for acetylcholinesterase: -   carbachol
-   methacholine (Provocholine)
-   both
-   neither
 
- Alkaloid agonist acting at muscarinic, cholinergic receptors: -   DFP
-   pilocarpine (Pilocar)
-   physostigmine (Antilirium)
-   ipratropium (Atrovent)
 
- Effective in treating both organophosphate and muscarine intoxication: -   nicotine
-   echothiophate (Phospholine)
-   atropine
-   pilocarpine (Pilocar)
 
- Cholinergic activity on stomach acid secretion -   increased
-   decreased
-   no changed
-   one of the others is right