Anesthesia Pharmacology Chapter 14:
General Anesthesia Practice Questions
Properties of inhalational anesthetics:
- More soluble in blood leads to more rapid induction.
- Anesthetic tension in the blood rises more rapidly for highly soluble drugs.
- Brain concentration of nitrous oxide rises rapidly.
- Rate of pulmonary blood flow significantly affects time to anesthetic equilibrium.
Accepted measure of anesthetic potency.
- lipid solubility
- speed of induction.
- presence of a "second gas effect"
- minimum alveolar concentration (MAC value)
Unpredictable hepatitis occurrence has been one factor that reduce the use of this inhalational anesthetic:
- isoflurane
- enflurane
- halothane
- desflurane
Very brief anesthetic effects of this barbiturate is explained by "rapid redistribution":
- nitrous oxide
- halothane
- thiopental
- fentanyl
Neurolept analgesia:
- propofol
- droperidol + fentanyl citrate
- ketamine
- enflurane + hydoxyzine