- Physiological effect NOT typically associated with opioids: -   constipation
-   constriction of biliary smooth muscle
-   enhanced renal function
-   limited direct cardiovascular effects
-   may prolong labor
 
- Mixed agonist-antagonist: -   naloxone (Narcan)
-   naltrexone (ReVia)
-   hydromorphone (Dilaudid)
-   nalbuphine (Nubain)
-   diphenoxylate (Lomotil)
 
- Used in treatment diarrhea: -   difenoxin
-    diphenoxylate (Lomotil)
-   loperamide (Imodium)
-   B & C
-   A,B & C
 
- Contraindications/caution for opioid use: -   patients with Addison's disease
-   patients with impaired pulmonary function
-   patients with head injury
-   B & C
-   A, B & C
 
- Useful drug(s) for opioid detoxification and maintenance of chronic relapsing heroin addict: -   methadone (Dolophine)
-   levomethadyl acetate
-   propoxyphene (Darvon)
-   A & B
-   A, B & C
 
- Effective antitussive(s) -   codeine
-   morphine
-   dextromethorphan
-   oxycodone (Roxicodone)
-   all the above
 
- Opioid antagonist with shortest duration of action: -   naloxone (Narcan)
-   nalmefene (Revex)
-   naltrexone (ReVia)
-   all about equal duration of action
-   these agents are not opioid antagonists
 
- Routes of opioid agonist administration: -   transdermal
-   patient-controlled analgesia (PCA)
-   intranasal
-   A & B
-   A, B & C
 
- Signs and symptoms of acute opioid withdrawal (abstinence syndrome) -   yawning
-   lacrimation
-   hyperventilation
-   diarrhea
-   all the above
 
- In obstetrical applications:opioid less likely to produce respiratory depression in the newborn -   meperidine (Demerol)
-   morphine