Pharmacology Practice Questions: Autonomic, Adrenergic Pharmacology

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Concerning localization of cell bodies of autonomic visceral afferents, which one(s) of the following statement(s) is/are correct?
1. In the case of spinal nerves, cell bodies are located in dorsal root ganglia.
2. In the case of cranial nerves, cell bodies are located in sensory ganglia.
3. Both
4. Neither
Choose (the) correct statement(s) concerning substance P:
1. Substance P is found in dorsal root ganglia.
2. Substance P has a prominent role in nociception.
3. Enkephalins tend to inhibit substance P release
4. Only answers A & B are correct
5. Only answers B & C are correct
6. Answers A, B & C are correct
What is the neurotransmitter typically released by postganglionic sympathetic fibers?
1. Glutamate
2. Norepinephrine
3. Acetylcholine
Nerve fibers of this branch of the autonomic nervous system tend to exhibit greater ramifications.
1. Parasympathetic
2. Sympathetic
3. Both are about equal in this regard
This autonomic ganglia is comprised of the celiac ganglia, superior mesenteric ganglia and aorticorenal and inferior mesenteric ganglia..
1. Terminal ganglia
2. Prevertebral ganglia
3. Paravertebral ganglia
Chromaffin cells are innervated by preganglionic fibers that release acetylcholine.
1. True
2. False
Concerning adrenergic effects on the eye, which one(s) of the following statements is/are correct?
1. Activation of alpha-1 receptors associated with the radial muscle of the iris causes mydriasis.
2. Activation of the beta-2 receptor associated with the ciliary muscle allows for accommodation of far vision.
3. Both
4. Neither
Increased cardiac automaticity could be associated with:
1. A decrease in the slope of phase 4 depolarization..
2. Activation of ß-1 cardiac receptors
3. A decrease in the likelihood of cardiac arrhythmia development.
4. None of the above
Factors that increase phase for depolarization include:
1. Mechanical stretch
2. Hypokalemic
3. Both
4. Neither
Sympathetic activity is especially critical for which one(s) of the following:
1. Temperature regulation
2. Glucose level regulation
3. Both
4. Neither
Interaction of which one(s)of the following with presynaptic receptors would probably increase neurally-mediated norepinephrine release.
1. Adenosine
2. Acetylcholine
3. Enkephalins
4. None of the above
This enzyme is responsible for catalyzing acetylcholine synthesis from precursors:
1. Pseudocholinesterase
2. Acetylcholinesterase
3. Dopamine ß hydroxylase
4. Choline acetyltransferase
5. Dopa decarboxylase
This enzyme catalyzes the rate determining step in catecholamine biosynthesis:
1. Phenylalanine hydroxylase
2. Tyrosine hydroxylase
3. Phenylethanolamine-N-methyltransferase
4. Monoamine oxidase (MAO)
5. Catechol-o-methyltransferase
Botulinum toxin would be least likely to affect cholinergic terminals at this site:
1. Peripheral ganglia
2. CNS
3. Neuromuscular junctions
4. Postganglionic parasympathetic endings
This cholinergic receptor system, upon activation, is coupled to a G protein system.
1. Nicotinic
2. Muscarinic