Anesthesia Pharmacology Practice Questions: Local Anesthetics

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Local anesthetics are:
1. Weak acids
2. Weak bases
3. Neither
Administration of this/these local anesthetic(s) cause vasoconstriction:
1. Bupivacaine
2. Ropivacaine
3. Both
4. Neither
These nerve fibers appear more sensitive to the action of local anesthetics with respect to reduced action potential propagation.
1. Large-diameter, rapidly conducting fibers
2. Small-diameter myelinated slowly conducting fibers
3. Both Fiber types are affected equally
Local anesthetics upon reaching the systemic circulation may result CNS effects including:
1. Initial CNS depression
2. Tremor
3. Clonic convulsions
4. A & B
5. B & C
6. A, B & C
This form of the local anesthetic preferentially interacts with sodium channels:
1. The unprotonated form (uncharged)
2. The protonated form (cationic, charged)
Which one(s) of the following local anesthetics may be administered to manage cardiac arrhythmias?
1. Procainamide
2. Lidocaine
3. Both
4. Neither
Local anesthetic effect(s) include(s):
1. Reduced myocardial conduction velocity
2. Reduced force of contraction
3. Both
4. Neither
Purpose(s) of adding epinephrine to the local anesthetic solution:
1. Increasing the duration of the local anesthetic effect through vasoconstriction.
2. Maintaining a similar rate of local anesthetic absorption into the general circulation and the rate of metabolism of the drug, thus reducing the likelihood of systemic toxicity
3. Both
4. Neither
Local anesthetics prevent nerve conduction principally by affecting this ion-channel:
1. Potassium
2. Sodium
3. Chloride
4. Calcium
Autonomic nerve fibers, small myelinated fibers mediating pain and temperature sensations and small unmyelinated C fibers transmitting pain sensations are blocked before larger myelinated fibers.
1. True
2. False