Anesthesia Pharmacology Practice Questions: Local Anesthetics

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Choose correct statement(s) concerning benzocaine:
1. Benzocaine is essentially used only as a topical anesthetic.
2. Current use of benzocaine has been decreasing due to possible induction of methemoglobinemia.
3. Both
4. Neither
Primary advantages of chloroprocaine include/includes:
1. Rapid onset
2. Short duration of action
3. Both
4. Neither
Bupivacaine blocks cardiac sodium channels during systole and dissociates from these channels more slowly compared to lidocaine during diastole.this property may contribute to bupivacaine cardiotoxicity.
1. True
2. False
Spinal anesthesia with bupivacaine is especially well-suited for outpatient/ambulatory surgical settings given its duration of action.
1. True
2. False
Bupivacaine-choose the INCORRECT statement(s):
1. Commonly used ester-typelocal anesthetic
2. Similar structure to lidocaine
3. Capable of producing extended anesthesia
4. Exhibits a property of providing more sensory compared to motor blockade
5. A & B
6. C & D
This agent, used in dental anesthesia, has likely eclipsed lidocaine as the likely standard drug.
1. Articaine
2. Mepivacaine
3. Prilocaine
4. Chloroprocaine
Lidocaine is less cardiotoxic than bupivacaine at equally-effective dose levels.
1. True
2. False
Large doses of chloroprocaine may be associated with extended sensory and motor block following epidural or subarachnoid administration. This effect has reduced the support for chloroprocaine clinical use.
1. True
2. False
This local anesthetic is considered unique in the amino-amide agents given that not only does the compound exhibit a thiophene ring but also an additional ester group which is a substrate for plasma esterases.
1. Benzocaine
2. Articaine
3. Bupivacaine
4. Chloroprocaine
Bupivacaine cardiotoxicity may also be mediated by the CNS given that bupivacaine injection to the medulla may induce malignant ventricular rhythm disorders.
1. True
2. False