Anesthesia Pharmacology: Diabetes Management Practice Questions
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Type 2 diabetes characterization:
Dysregulation of glucose homeostasis
Impairment of both insulin secretion and action
Both
Neither
Being overweight or obese is frequently associated with type 2 diabetes occurring in about:
25% of affected individuals
40% of affected individuals
60% of affected individuals
80% of affected individuals
Greater than 95% of affected individuals
Effectiveness of insulin action in the maintenance of appropriate plasma glucose levels depends upon which one(s) of the following:
Plasma insulin levels as determined by islet beta cell activity.
Insulin sensitivity an important target tissue such as liver, fat, and skeletal muscle.
Both
Neither
Type 2 diabetes exhibits a significant,strong genetic contribution.
True
False
Should an individual have a diabetic parent or sibling, there is a relative 4-fold increase disease risk.
True
False
Concerning reduced islet beta cell sensitivity to glucose in type 2 diabetes:
Responsiveness to other "insulinotropic" gastrointestinal hormones is retained.
Responsiveness to neural signaling is retained.
Both
Neither
Reduced sensitivity of the beta-cell to glucose and losses of responsiveness to other stimuli results in:
A slowing of the natural increase in blood glucose following meals.
A rapid increase in hepatic glucose release during fasting.
Both
Neither
In most individuals with type 2 diabetes increasing treatment is required to maintain glucose control as a result of a progressive decrease in Beta-cell mass and function.
True
False
In type 2 diabetes dysregulation of glucagon secretion is observed, with excessive glucagon secretion common.
True
False
Insulin sensitivity is reflected in the amount of glucose removed from blood following a fixed insulin dose.