Anesthesia Pharmacology: Vasoactive Peptide Practice
Questions
Choose the correct answer for each question.
1 / 10
Concerning the intrarenal baroreceptor receptor pathway in regulation of renin:
- Increases or decreases in preglomerular vessel blood pressure can change renin release..
- Changes in renal perfusion pressure influence renin release.
- Both
- Neither
Concerning the ß1 adrenergic receptor and renin release:
- Postganglionic sympathetic nerves releasing norepinephrine activates juxtaglomerular ß1 receptors.
- Administration of ß receptor antagonists (blockers) increases renin secretion and plasma renin activity
- Both
- Neither
Angiotensinogen is the renin substrate.
- True
- False
Effect(s) associated with angiotensin 1 receptor activation:
- Vasoconstriction
- Vascular smooth muscle cellular inflammation
- Cardiac hypertrophy
- Reduced fibrosis
- A & B
- A & C
- A, B & C
- A, B, C, & D
Effect(s) associated with angiotensin 2 receptor activation:
- Vasodilation
- Anti-proliferation
- Diminished oxidative stress
- Antifibrotic activity
- Reduced inflammation
- A, B & C
- A, B & D
- A, B, C, D & E
Example of a selective ACE (angiotensin-converting enzyme) inhibitor:
- Losartan
- Aliskiren
- Enalapril
- Candesartan Cilexetil
Which one(s) of the following renin-angiotensin system inhibitors is/are prodrugs?
- Eprosartan
- Candesartan Cilexetil
- Enalapril
- A & B
- B & C
- A & C
- A, B & C
Which one(s) of the following concerning angiotensin II receptors is/are correct?
- Angiotensin II receptors exhibited limited distribution, confined mainly to the CNS.
- Angiotensin II receptors are localized on plasma membranes and are categorized is G protein-coupled system
- Both
- Neither
This type of angiotensin II receptor subtype when activated resultant vasodilation.
- AT1
- AT2
Most action so far described of angiotensin II occur as a result of AT1 receptor activation.
- True
- False