Medical Pharmacology Chapter 14:  General Anesthesia

Previous Page

Next Page

Section Table of Contents

Site Table of Contents

Fulminant halothane Hepatitis

 

  • The liver is flabby, soft, friable similar to any acute viral hepatitis. It was called in the past 'acute yellow atrophy'.

  • Dr. Emilio Orfei, Loyola University Chicago, Stritch School of Medicine

 

  • Massive centrolobular necrosis. Notice the central vein and necrosis of liver cells in all three zones of the lobule. A few cloisters of hepatocytes in form of cords and pseudo-ductules remain in the periphery of the lobule.Notice absence of inflammatory reaction and no endophlebites of the vein as it would be seen in viral hepatitis."

  • Dr. Emilio Orfei,  Loyola University Chicago, Stritch School of Medicine

 

Kennedy, S.K. and Longnecker, D.E., History and Principles of Anesthesiology In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, p 313.

White, P. F. "Anesthesia Drug Manual", W.B. Saunders Company, 1996, p. 249.

 

Kennedy, S.K. and Longnecker, D.E., History and Principles of Anesthesiology In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, p 319 - 321.

Stoelting, R.K., "Inhaled Anesthetics", in Pharmacology and Physiology in Anesthetic Practice, Lippincott-Raven Publishers, 1999, pp 36-76

 

Stoelting, R.K., "Inhaled Anesthetics", in Pharmacology and Physiology in Anesthetic Practice, Lippincott-Raven Publishers, 1999, pp 36-76

White, P. F. "Anesthesia Drug Manual", W.B. Saunders Company, 1996. p.248

 

Kennedy, S.K. and Longnecker, D.E., History and Principles of Anesthesiology In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, p 315 - 317.

White, P. F. "Anesthesia Drug Manual", W.B. Saunders Company, 1996, p. 250.

Stoelting, R.K., "Inhaled Anesthetics", in Pharmacology and Physiology in Anesthetic Practice, Lippincott-Raven Publishers, 1999, pp 36-76

White, P. F. "Anesthesia Drug Manual", W.B. Saunders Company, 1996, p. 248.

 

 

Stoelting, R.K., "Inhaled Anesthetics", in Pharmacology and Physiology in Anesthetic Practice, Lippincott-Raven Publishers, 1999, pp 36-76 White, P. F. "Anesthesia Drug Manual", W.B. Saunders Company, 1996.

Previous Page

Next Page

Section Table of Contents

Site Table of Contents