Cefuroxime
  • Effective in community-acquired pneumonia (especially if causitive agent may be ß-lactamase producing H. influenzae or Klebsiella pneumoniae.
  • Only second-generation agent to cross the blood-brain-barrier, but third-generation agents ceftriaxone or cefotaxime are more effective in treating menningitis.
Chambers, H.F., Hadley, W. K. and Jawetz, E. Introduction to Antimicrobial Agents in Basic and Clinical Pharmacology, (Katzung, B. G., ed) Appleton-Lange, 1998, p 734.