Active against gram-positive
cocci; these agents have an extended
gram-negative spectrum compared to first
generation drugs.
Active against ß-lactamase
producing H.influenzae
Good activity against anaerobes;
effective in mixed-infections (e.g. peritonitis)
Chambers, H.F., Hadley, W. K.
and Jawetz, E. Introduction to Antimicrobial Agents in
Basic and Clinical Pharmacology, (Katzung, B. G., ed)
Appleton-Lange, 1998, p. 734.
Active against gram-positive
cocci; these agents have an extended
gram-negative spectrum compared to first
generation drugs.