Life Cycle T. gondii
  • "Members of the cat family (Felidae) are the only known definitive hosts for the sexual stages of T. gondii and thus are the main reservoirs of infection. 
  • Cats become infected with T. gondii by carnivorism. 
  • After tissue cysts or oocysts are ingested by the cat, viable organisms are released and invade epithelial cells of the small intestine where they undergo an asexual followed by a sexual cycle and then form oocysts, which are then excreted. 
  • The unsporulated oocyst takes 1 to 5 days after excretion to sporulate (become infective). 
  • Although cats shed oocysts for only 1 to 2 weeks, large numbers may be shed. 
  • Oocysts can survive in the environment for several months and are remarkably resistant to disinfectants, freezing, and drying, but are killed by heating to 70oC for 10 minutes.
  • Human infection may be acquired in several ways:
    • 1) ingestion of undercooked infected meat containing Toxoplasma cysts;
    • 2) ingestion of the oocyst from fecally contaminated hands or food;
    • 3) organ transplantation or blood transfusion;
    • 4) transplacental transmission;
    • 5) accidental inoculation of tachyzoites. 
    • The parasites form tissue cysts, most commonly in skeletal muscle, myocardium, and brain; these cysts may remain throughout the life of the host."- CDC (used with permission, public domain)
  • http://www.dpd.cdc.gov/DPDx/HTML/Toxoplasmosis.htm