Medical Pharmacology Chapter 2: Pharmacokinetics Practice Questions

Choose the correct answer for each question.

- Constant Infusion: the infusion rate for Drug X is 150 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L: What is the Css?
- 0.082 ug/ml
- 4.89 ug/ml
- 4,89 mg/ml
- 9.8 ug/ml
- 0.0489

- Constant Infusion: the infusion rate for Drug X is 150 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 12L (volume of the extracellular space): What is the Css?
- 4.9 ug/ml
- 9.7 ug/ml
- 16.2 ug/ml
- 14.6 ug/ml
- 20 ug/ml

- Constant Infusion: the infusion rate for Drug X is 300 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L: What is the Css?
- 4.9 ug/ml
- 9.7 ug/ml
- 16.2 ug/ml
- 14.6 ug/ml
- none of the above

- Constant Infusion: the infusion rate for Drug X is 450 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L: What is the Css?
- 4.9 ug/ml
- 9.7 ug/ml
- 16.2 ug/ml
- 14.6 ug/ml
- 19 ug/ml

- Constant Infusion: the infusion rate for Drug X is 300 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L: How long does it take to reach 50% of Css?
- 3 hours
- 9 hours
- 15 hours
- 24 hours
- 60 hours

- Constant Infusion: what would be the infusion rate for Drug X to attain a steady-state concentration of 25 ug/ml?; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L
- 25 ug/min
- 300 ug/min
- 600 ug/min
- 760 ug/ml
- 0.019 ug/ml

- Constant Infusion: the infusion rate for Drug X is 300 ug/min; half-life for elimination is 15 hours; ke = 0.046/hr; Vd = 40L: How long does it take to reach 90% of Css?
- 7.5 hours
- 15 hours
- 30 hours
- 50 hours
- 60 hours