Medical Pharmacology: Immunopharmacology Practice Flashcards

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Question # 1 (Multiple Choice) Structural analog/antimetabolite: cytotoxic immunosuppressive drug:

    A) vincristine
    B) cyclophosphamide
    C) azathioprine
    D) none of the above

Question # 2 (Multiple Choice) Immunomodulatory sedative drugs used in the management of some forms of leprosy; also effective in managing skin manifestations of lupus erythematosus

    A) tacrolimus
    B) cyclophosphamide
    C) thalidomide
    D) buproprion
    E) diazepam

Question # 3 (Multiple Choice) Drug of choice in treating autoimmune hemolytic anemia:

    A) cyclophosphamide plus factor XIII
    B) Rho(D) immune globulin
    C) prednisone
    D) OKT3 monoclonal antibody
    E) cyclosporine

Question # 4 (Multiple Choice) Interferes with cell cycle of activated lymphoid cells;example of the first class of hormonal agents recognized have lympholytic properties:

    A) cyclosporine
    B) tacrolimus
    C) IFN-alpha
    D) dexamethasone
    E) 15-desoxyspergualin

Question # 5 (Multiple Choice) Useful in management of idiopathic thrombocytopenic purpura refractory to prednisone

    A) dactinomycin
    B) vincristine
    C) cyclophosphamide
    D) azathioprine
    E) all of the above

Question # 6 (Multiple Choice) Drug of choice in treating hemolytic anemia of the newborn:

    A) cyclosporine
    B) prednisone
    C) OKT3 monoclonal antibody
    D) tacrolimus
    E) Rho(D) immune globulin

Question # 7 (Multiple Choice) Clinical uses of interferon:

    A) cancer treatment
    B) multiple sclerosis
    C) both
    D) neither

Question # 8 (True/False) Type 1 hypersensitivity: cross-linking of membrane-bound IgE on blood basophils or tissue mast cells by antigen

    A) true
    B) false

Question # 9 (Multiple Choice) immunomodulating agents:

    A) thymosin
    B) interferon beta
    C) interferon-gamma
    D) TNF alpha
    E) all the above

Question # 10 (True/False) Class 1 MHC molecules present mainly fragments of cellular antigens

    A) true
    B) false

Question # 11 (Multiple Choice) Inhibits antigen recognition of B-cell

    A) prednisone
    B) azathioprine
    C) methotrexate
    D) Rho(D) immune globulin
    E) tacrolimus

Question # 12 (Multiple Choice) Antilymphocyte antibodies:

    A) binds to the surface of T cells
    B) acts mainly on small, long-lived peripheral lymphocytes
    C) may be used in induction of immunosuppression
    D) may be obtained by hybridoma technique for monoclonal antibody generation
    E) all of the above

Question # 13 (Multiple Choice) Clinical uses of immunosuppressive drugs:

    A) organ transplantation
    B) hemolytic disease of the newborn
    C) autoimmune disorders
    D) A & C
    E) A, B & C

Correct Answers

1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13






































Question # 1 (Multiple Choice) Structural analog/antimetabolite: cytotoxic immunosuppressive drug:

Answer: (C) azathioprine

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Question # 2 (Multiple Choice) Immunomodulatory sedative drugs used in the management of some forms of leprosy; also effective in managing skin manifestations of lupus erythematosus

Answer: (C) thalidomide

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Question # 3 (Multiple Choice) Drug of choice in treating autoimmune hemolytic anemia:

Answer: (C) prednisone

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Question # 4 (Multiple Choice) Interferes with cell cycle of activated lymphoid cells;example of first-class hormonal agents recognized have lympholytic properties:

Answer: (D) dexamethasone

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Question # 5 (Multiple Choice) Useful in management of idiopathic thrombocytopenic purpura refractory to prednisone

Answer: (B) vincristine

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Question # 6 (Multiple Choice) Drug of choice in treating hemolytic anemia of the newborn:

Answer: (E) Rho(D) immune globulin

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Question # 7 (Multiple Choice) Clinical uses of interferon:

Answer: (C) both

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Question # 8 (True/False) Type 1 hypersensitivity: cross-linking of membrane-bound IgE on blood basophils or tissue mast cells by antigen

Answer: True

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Question # 9 (Multiple Choice) immunomodulating agents:

Answer: (E) all the above

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Question # 10 (True/False) Class 1 MHC molecules present mainly fragments of cellular antigens

Answer: True

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Question # 11 (Multiple Choice) Inhibits antigen recognition of B-cell

Answer: (D) Rho(D) immune globulin

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Question # 12 (Multiple Choice) Antilymphocyte antibodies:

Answer: (E) all of the above

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Question # 13 (Multiple Choice) Clinical uses of immunosuppressive drugs:

Answer: (E) A, B & C

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