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Nursing Pharmacology Practice Questions: Antifungal Drugs
Matching exercise
Pick the best match from the options (down arrow)
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fluconazole
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
itraconazole
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
griseofulvin
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
terbinafine
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
flucytosine
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
ketoconazole
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
amphotericin B
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
nystatin
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
naftifine
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
miconazole
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fungicidal;inhibits squalene epoxidase;dermatophytoses- onychomycosis;
cryptococcus neoformans; no monotherapy-resistance
gynecomastia and menstrual irregularities
most potent of available azoles
topical polyene macrolide activity:most Candida species;
topical azole; vulvovaginal candidiasis
allylamine available as a topical cream - tinea cruris
broadest spectrum of action
derived from Penicillum; systemic dermatophytosis treatment
azole with highest CSF:Serum ratio
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