Nursing Pharmacology:  Antiviral Drugs

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Entry Inhibitors

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References

  1. Acheson NH  Chapter 1 (in Acheson NH,  Fundamentals of molecular virology, 2nd edition) p. 13 2011.

  2. Wang F Kieff E Medical Viriology, Chapter 177 Section 11:  Viral Diseases:  General Considerations (in Harrison's Principles of Internal Medicine, 18th edition, Longo DF Fauci AS Kasper DL Hauser SL Jameson JL Loscalzo J, eds) McGraw-Hill, New York, 2012, pp 1432-1433.

  3. Jones M HIV Membrane Fusion Panel (first two steps, see original reference for all steps). "1.  Initial interaction between gp120 and CD4. 2. Conformation changes in gp120 allows for secondary interaction with CCR5.http://en.wikipedia.org/wiki/HIV#mediaviewer/File:HIV_Membrane_fusion_panel.svg ; http://en.wikipedia.org/wiki/HIV

  4. Karlsson GB Fouchier RAM Phogat S Burton DR Sodroski J Wyat RT Nature Reviews Micobiology 6, 143-155 (February 2008). http://www.nature.com/nrmicro/journal/v6/n2/fig_tab/nrmicro1819_F4.html

  5. Fusion of virus membrane with host cell membrane ViralZone, Swiss Institute of Bioinformatics © ViralZone 2011

  6. Flexner C Chapter 59.  Antiretroviral Agents and Treatment of HIV Infection (in Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12 e, Brunton LL Chabner BA Knollmann BC, eds) The McGraw-Hill Companies, Inc, 2011.

  7. Eckert DM Kim PS Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region. PNAS (USA) 98(20):  11187-11192, September 25, 2001

  8. Harrison S (Harvard) Part 2:  Viral membrane fusion, iBiology (IBioSeminars:  Seminars from the World's Top Biologists, https://www.youtube.com/channel/UCsvqEZBO-kNmwuDBbKbfL6A);  https://www.youtube.com/watch?v=qcepGvFUM38

  9. LaBonte J Lebbos J Kirkpatrick nature Reviews Drug Discovery 2, 345-346 (May 2003). (Slight modification of Fig. 1) http://www.nature.com/nrd/journal/v2/n5/fig_tab/nrd1091_F1.html; Original figure attribution:  Kilby JM Hopkins S Venetta TM DiMassima B Cloud GA Lee JY Alldredge L Hunter E Lambert D Bolognesi D Matthews T Johnson MR Nowak MA Shaw GM Saag MS Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat. Med 4(11): 1302-1307, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9809555

  10. Tsibris AMN Hirsch MS Chapter 130 Antiretroviral Therapy for Human Immunodeficiency Virus Infection in Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 8e (Bennett JE Bolin R Blaser, eds) Elsevier, Inc/Saunders 2015, online version.

  11. Fuzeon Clinical Pharmacology:  RxList (The Internet Drug Index) http://www.rxlist.com/fuzeon-drug/clinical-pharmacology.htm

  12. Safrin S Chapter 49:  Antiviral Agents:  Antiretroviral Agents in Basic & Clinical Pharmacology 13e (Katzung BG Trevor AJ, eds) 2015, online edition.

  13. AIDSinfo:  Guidelines for the Use of Antriretroviral Agents in HIV-1-Infected Adults and Adolescents https://aidsinfo.nih.gov/guidelines (2015)

  14. Gupta A Chavva S Rana N HIV Envelope Glycoprotein:  Fusion and Inhibition (Video 13); http://education.pdb.org/videochallenge/index.php ; https://www.youtube.com/watch?v=4ae9FAU_q8Q

  15. Fauci A HIV/AIDS in 2014:  Progress and Priorities ("Anthony Fauci MD, Director of the National Institute on Allergy and Infectious Diseases, will discuss the present and future entironment for battling HIV/AIDS. https://www.youtube.com/watch?v=ZqS-6Bwm99w

  16. Correll T, PharmD, BCPS, Clinical Pharmacy Specialist, Infectious Disease/HIV. University of North Carolina Hospitals, November 2006 http://www.slideshare.net/flaviog/11-1822498

 

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