Medical Pharmacology Chapter 38: Antiparasitic Agents

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Cysts of Entamoeba histolytica/dispar

G H I J K
  • Cysts of Entamoeba histolytica/dispar.  Line drawing (G), wet mounts stained with iodine (H, I) and permanent preparations stained with trichrome (J, K).

  •  The cysts are usually spherical and often have a halo (H, I). 

  •  Mature cysts have 4 nuclei. The cyst in H appears uninucleate while in I, J and K 2 to 3 nuclei are visible in the focal plane (the fourth nucleus is coming into focus in J). 

  •  The nuclei have characteristically centrally located karyosomes, and fine, uniformly distributed peripheral chromatin. 

  •  The cysts in I, J and K contain chromatoid bodies with the one in J being particularly well demonstrated, with typically blunted ends.  Entamoeba histolytica cysts usually measure 12 to 15 µm

  • Courtesy of the Division of Parasitic Diseases at the National Center for Infectious Diseases, Centers for Disease Control and Prevension (public domain)

  • http://www.dpd.cdc.gov/DPDx/HTML/Amebiasis.htm

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