Medical Pharmacology Chapter 16:  Pharmacology of Antipsychotics Drugs

 

Section Table of Contents

Site Table of Contents

Previous Page

Table of Contents

Schizophrenia

Lithium

 

 

 

Schizophrenia

 

 

 

Dopamine

Antipsychotic drugs-chemical classifications

 

 

Section Table of Contents

Site Table of Contents

Previous Page

Basic Antipsychotic Drug Pharmacology

 Adverse Effects/Reactions

Section Table of Contents

Site Table of Contents

Previous Page

Clinical Indications for Antipsychotic Drugs

Antipsychotic Drug Classes: Potencies and Toxicities

Chemical Class

Drug

Potency

Extrapyramidal Effects

Sedation

Alpha blockade: hypotension

Phenothiazine: aliphatic

Chlorpromazine (Thorazine)

Phenothiazine: piperazine

Fluphenazine (Prolixin)

Thioxanthene

Thiothixene (Navane)

Butyrophenone

Haloperidol (Haldol)

Dibenzodiazepine

Clozapine (Clozaril)

Thienobenzodiazepine

Olanzapine (Zyprexa)

--low

--very high

adapted from Table 29-1: Potter, W. Z. and Hollister, L.E.,Antipsychotic Agents and Lithium, in Basic and Clinical Pharmacology, (Katzung, B. G., ed) Appleton-Lange, 1998, p 468.

 

 

Some Antipsychotics Drug Classifications

Phenothiazines

  • Vhlorpromazine

  • Thioridazine

  • Fuphenazine

Buterophenones

  • Haloperidol

Dibenzodiazepine

  • Clozapine

Lithium

Lithium Pharmacology

Lithium Clinical Pharmacology

 Adverse Effects

 
 
 
 

Section Table of Contents

Site Table of Contents

Previous Page