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Valvular Disease

25 cases spanning medical management and surgical-threshold decisions across the major native and prosthetic valve lesions.

Cardiovascular Valvular Disease
Case 0122

Asymptomatic Severe Aortic Stenosis: What the Exercise Test Changed

A single patient whose aortic stenosis has produced no symptoms he's noticed, and one finding on formal testing that changes how seriously “no symptoms” should be taken.

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Cardiovascular Valvular Disease
Case 0123

Referring for Early Mitral Repair Ahead of the Guideline Threshold

A single patient whose mitral valve anatomy is exactly the kind current evidence says benefits most from earlier repair, sitting just short of the numbers that would make that decision automatic.

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Cardiovascular Valvular Disease
Case 0124

Mechanical or Bioprosthetic: A Valve Choice Shaped by His Job

A single patient for whom the medical evidence doesn't clearly favor one valve type over the other, and whose daily work turns out to be the more decisive factor.

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Cardiovascular Valvular Disease
Case 0125

Balloon Valvuloplasty or Replacement: Reading a Borderline Mitral Valve

A single patient whose mitral valve anatomy sits close enough to the line between two very different treatment paths that one additional imaging study is needed before either can be chosen with confidence.

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Cardiovascular Valvular Disease
Case 0126

Closer Surveillance for Asymptomatic Aortic Regurgitation, Given the Valve's Cause

A single patient whose aortic regurgitation hasn't crossed any guideline threshold yet, where one detail about its underlying cause changes how closely it should be watched.

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Cardiovascular Valvular Disease
Case 0127

Endocarditis Prophylaxis After a Repaired, Not Replaced, Mitral Valve

A single patient caught between her dental office's longstanding routine and her cardiologist's current guidance, over a valve procedure that current evidence treats differently than most people assume.

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Cardiovascular Valvular Disease
Case 0128

Paravalvular Leak After TAVR: Close It Now or Watch It

A single patient whose new post-TAVR finding carries real long-term risk, found on a routine echo well before any symptom appeared.

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Cardiovascular Valvular Disease
Case 0129

Whether to Address the Tricuspid Valve During Mitral Surgery

A single patient whose mitral repair is the clear priority, with a second, less severe valve problem making the actual scope of the operation a genuine question.

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Cardiovascular Valvular Disease
Case 0130

Valve Surgery Timing for Endocarditis After a Recent Stroke

A single patient whose endocarditis meets the criteria for early surgery, with a five-day-old stroke complicating exactly how early “early” should be.

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Cardiovascular Valvular Disease
Case 0131

Empiric Antibiotics for Endocarditis When the Cultures Stay Negative

A single patient whose clinical picture is convincing for endocarditis and whose blood cultures won't confirm it, with an occupational history that shifts the differential toward organisms routine coverage doesn't treat.

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Cardiovascular Valvular Disease
Case 0140

Mitral Stenosis Worsening in Pregnancy: Medical Management or Balloon Valvuloplasty Now?

Her valve area has moved from moderate to severe since this pregnancy began, and the team is weighing how far rate control and diuresis can carry her against a real, narrowing window for a safer procedure.

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Cardiovascular Valvular Disease
Case 0141

Paradoxical Low-Gradient Severe Aortic Stenosis: Correcting Flow Before Trusting the Numbers

Her valve area calculates as severe, but her gradient doesn't match it — and two correctable findings, a diuretic dose set years ago and new anemia, may be suppressing her flow state enough to explain the mismatch.

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Cardiovascular Valvular Disease
Case 0142

Bicuspid Aortic Valve With Borderline Root Growth: Does the Marfan Evidence for Medical Therapy Apply?

His aortic root is still below the surgical threshold, but its growth rate over two years is faster than expected — and the medical therapy that might slow it further has much of its evidence built in a different condition.

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Cardiovascular Valvular Disease
Case 0143

Right-Sided Endocarditis From Injection Drug Use: Why Outpatient Antibiotic Step-Down Isn't the Default Here

His infection likely doesn't need surgery, and the antibiotics that will cure it are well established — the actual disagreement is how to deliver a month or more of inpatient treatment to a man who has already left before completing one.

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Cardiovascular Valvular Disease
Case 0144

Anticoagulation Bridging for a Mechanical Mitral Valve Before Semi-Urgent Surgery

The trial evidence on anticoagulation bridging was built almost entirely in atrial fibrillation, and explicitly excluded the mechanical heart valve population he's actually in.

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Cardiovascular Valvular Disease
Case 0145

Functional Mitral Stenosis From Annular Calcification: Medical Management or Transcatheter Replacement?

Balloon valvuloplasty won't work on a calcified annulus, and conventional surgery carries real risk in this anatomy — leaving medical therapy and an emerging transcatheter option as the actual choice.

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Cardiovascular Valvular Disease
Case 0146

Secondary Mitral Regurgitation in HFrEF: Optimizing Heart Failure Therapy Before TEER

COAPT and MITRA-FR reached different conclusions about this exact procedure, and one leading explanation is how thoroughly each trial's patients had their heart failure therapy optimized first.

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Cardiovascular Valvular Disease
Case 0147

Bicuspid Valve Aortic Regurgitation in a Young Adult: Earlier Repair or Continued Surveillance?

His anatomy still favors a durable valve repair today, but standard surgical thresholds haven't been met yet — a tension between operating while the window is open and waiting for a clearer indication.

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Cardiovascular Valvular Disease
Case 0148

Endocarditis Prophylaxis After Ring-Supported Mitral Repair: Does the Guideline Apply?

Her own valve tissue was preserved during her repair, but the annuloplasty ring supporting it is implanted material — and the AHA names that material explicitly, even as the underlying evidence for prophylaxis at all remains thin.

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Cardiovascular Valvular Disease
Case 0149

Possible Endocarditis With Negative Cultures and a Non-Diagnostic Echo: How Long to Wait?

He meets a real clinical picture for endocarditis, but neither of the two major diagnostic criteria has been confirmed yet — and his occupation points toward organisms that need their own specific tests before starting empiric antibiotics blindly.

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Cardiovascular Valvular Disease
Case 0181

Failing Bioprosthetic Aortic Valve: Valve-in-Valve or a Second Sternotomy

A decade-old surgical bioprosthesis is failing on schedule, but its small original size turns the obvious-seeming transcatheter fix into its own separate risk. The disagreement is about which uncertainty is worth accepting.

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Cardiovascular Valvular Disease
Case 0182

Recurrent Mitral Regurgitation After Repair: Four Years Later, Moderate Again

A durable-looking mitral repair has quietly slipped back to moderate regurgitation in a patient who feels nothing at all. The disagreement is about whether to act on a finding this early or wait for it to declare itself further.

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Cardiovascular Valvular Disease
Case 0183

Aortic Stenosis and Mitral Regurgitation Together: Two Patients, Discordant Severity

Two patients each carry a stenotic aortic valve and a leaking mitral valve at the same time, but in neither case do the two lesions carry equal weight. The disagreement in each case is about which valve is actually driving symptoms and risk, and whether treating it changes how the other one should be read.

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Cardiovascular Valvular Disease
Case 0188

Prosthetic Valve Endocarditis: A Lower Threshold for Surgery, But How Much Lower

A new paravalvular leak on a mechanical mitral valve, five days into treatment for a favorable, antibiotic-susceptible infection. The disagreement is about whether that single mechanical finding is itself enough to schedule surgery now.

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Cardiovascular Valvular Disease
Case 0189

Rheumatic Mitral Regurgitation in a Twenty-Six-Year-Old: Repair, Mechanical Valve, or Bioprosthesis

Severe rheumatic mitral regurgitation in a woman planning a pregnancy within the next year or two turns an ordinary valve-choice conversation into one where a cardiac decision and a reproductive one carry equal, unresolved weight.

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